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Research and review articles are invited for publication in September - October 2026 (Volume 19, Issue 1) Submit manuscript

Evaluation of the efficacy of Saplint plus roll-on in the treatment of acute myalgia: A prospective, open-label, single-arm clinical trial

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  • Evaluation of the efficacy of Saplint plus roll-on in the treatment of acute myalgia: A prospective, open-label, single-arm clinical trial

Anjali KA 1, Sibi Narayanan 2, *, Anu Joy 3, Maneesha KS 4, Sreedevi AP 5, Reeshma CR 6, and Adithya Peethambara Panicker 7

1 Scientific Content Strategist, Sitaram Ayurveda Pvt. Ltd., Kerala, India.
2 Manager, R&D Department, Sitaram Ayurveda Pvt. Ltd., Kerala, India.
3 Research Officer, R&D Department, Sitaram Ayurveda Pvt. Ltd., Kerala, India.
4 Jr. Officer, R&D Department, Sitaram Ayurveda Pvt. Ltd., Kerala, India.
5 Research Officer, R&D Department, Sitaram Ayurveda Pvt. Ltd., Kerala, India.
6 Jr. Chemist, R&D Department, Sitaram Ayurveda Pvt. Ltd., Kerala, India.
7 AGM-M&I, Sitaram Ayurveda Pvt. Ltd., Kerala, India.
Research Article
Magna Scientia Advanced Biology and Pharmacy, 2025, 15(01), 001-007
Article DOI: 10.30574/msabp.2025.15.1.0038
DOI url: https://doi.org/10.30574/msabp.2025.15.1.0038
Received on 16 March 2025; revised on 03 May 2025; accepted on 05 May 2025
Background: Myalgia, or muscle pain, is a prevalent condition with diverse etiologies ranging from overuse to viral infections. Conventional treatments, while effective, often carry risks of adverse effects with prolonged use. Saplint Plus Roll-On, an Ayurvedic formulation, offers a non-invasive, herbal approach to pain relief.
Objective: To evaluate the efficacy of Saplint Plus Roll-On in the management of acute myalgia over a 7-day period.
Methods: A single-arm, open-label, prospective clinical trial was conducted involving 100 patients diagnosed with acute myalgia. Participants applied Saplint Plus Roll-On three times daily. Efficacy was assessed using the Visual Analog Scale (VAS), Patient Global Assessment, and Modified Oswestry Disability Index (ODI).
Results: The mean VAS score reduced from 7.5 at baseline to 2.0 on Day 7 (73% reduction, p < 0.01). The mean ODI score improved from 45.2 to 25.3 (p < 0.01). No adverse events were reported.
Conclusion: Saplint Plus Roll-On significantly reduced pain and improved functional ability in patients with acute myalgia, offering an effective alternative to conventional analgesics.
Acute Myalgia; Saplint Plus Roll-On; Ayurvedic Formulation; Pain Reduction; Visual Analog Scale; Oswestry Disability Index
https://msabp.magnascientiapub.com/sites/default/files/fulltext_pdf/MSABP-2025-…

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Anjali KA, Sibi Narayanan, Anu Joy, Maneesha KS, Sreedevi AP, Reeshma CR and Adithya Peethambara Panicker. Evaluation of the efficacy of Saplint plus roll-on in the treatment of acute myalgia: A prospective, open-label, single-arm clinical trial. Magna Scientia Advanced Biology and Pharmacy, 2025, 15(1), 001-007. Article DOI: https://doi.org/10.30574/msabp.2025.15.1.0038

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