Department of Computer Science, Saint Louis University, USA.
Received on 09 February 2026; revised on 15 March 2026; accepted on 18 March 2026
The growing burden of chronic diseases including cardiovascular disorders, diabetes, respiratory illnesses, and cancer continues to exert significant pressure on healthcare systems across the United States. Effective population health management requires advanced analytical tools capable of identifying risk patterns, forecasting disease prevalence, and optimizing healthcare resource allocation. Machine learning–driven population health analytics has emerged as a transformative approach for addressing these challenges by leveraging large-scale healthcare datasets, electronic health records, insurance claims, and socio-demographic indicators. At a broader level, machine learning techniques enable healthcare systems to detect complex nonlinear relationships among clinical, behavioral, environmental, and socioeconomic determinants of health. These capabilities facilitate early identification of high-risk populations and support predictive modeling of chronic disease trajectories across diverse communities. At a more focused level, predictive algorithms including random forests, gradient boosting, and deep neural networks can be applied to estimate future chronic disease burden and guide strategic distribution of healthcare resources such as hospital capacity, preventive care programs, and workforce planning. By integrating geospatial analytics and real-time health surveillance, machine learning models further enhance the ability of public health agencies to prioritize interventions in underserved regions and mitigate disparities in healthcare access. Consequently, machine learning–driven population health analytics provides a data-informed framework for proactive healthcare planning, enabling policymakers and healthcare administrators to improve clinical outcomes, optimize resource utilization, and strengthen the resilience of the United States healthcare system.
Machine learning; Population health analytics; Chronic disease prediction; Healthcare resource allocation; Predictive healthcare modeling; United States healthcare system
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Olawale Ajibola Ashaolu. Machine learning–driven population health analytics for predicting chronic disease burden and healthcare resource allocation in the United States. Magna Scientia Advanced Biology and Pharmacy, 2026, 17(02), 008-032. Article DOI: https://doi.org/10.30574/msabp.2026.17.2.0023