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Research and review articles are invited for publication in September - October 2026 (Volume 19, Issue 1) Submit manuscript

Problems with the variants or quasi-species of the Hepatitis B virus (HBV) in treatment

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  • Problems with the variants or quasi-species of the Hepatitis B virus (HBV) in treatment

Angel San Miguel Rodríguez 1, Angel San Miguel Hernández 2, *, Julia San Miguel Rodríguez 1 and Maria San Miguel Rodríguez 1

1 Research Unit Service. Río Hortega University Hospital. Valladolid. Spain.
2 Clinical Analysis Service. Río Hortega University Hospital. International University of La Rioja (UNIR). Spain
 
Review Article
Magna Scientia Advanced Biology and Pharmacy, 2021, 03(01), 013-018
Article DOI: 10.30574/msabp.2021.3.1.0029
DOI url: https://doi.org/10.30574/msabp.2021.3.1.0029
Received on 07 June 2021; revised on 09 July 2021; accepted on 11 July 2021
 
The HBV genome has a very high mutation rate, which is why it is considered a highly variable virus, being able to produce different variants or quasi-species in the same host, differentiated by small mutations that favor the oncogenic potential of the virus, in addition to attenuating the immunogenicity and antigenicity.
There are a large number of epidemiological findings and studies that suggest a relationship between genotypes and pre-core / core variants of the hepatitis B virus with the clinical course of infection and the response to different antiviral treatments.
 
Hepatitis B; HBV; Virus; Mutations; Variants; Quasi-species
 
https://msabp.magnascientiapub.com/sites/default/files/fulltext_pdf/MSABP-2021-…

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Angel San Miguel Rodríguez, Angel San Miguel Hernández, Julia San Miguel Rodríguez and Maria San Miguel Rodríguez. Problems with the variants or quasi-species of the Hepatitis B virus (HBV) in treatment. Magna Scientia Advanced Biology and Pharmacy, 2021, 3(1), 013-018. Article DOI: https://doi.org/10.30574/msabp.2021.3.1.0029

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