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Research and review articles are invited for publication in September - October 2026 (Volume 19, Issue 1) Submit manuscript

p-Toluene sulfonic acid, C-DEB, and chronic ulcers: chemical, toxicological and clinical analysis and therapeutic prospects

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  • p-Toluene sulfonic acid, C-DEB, and chronic ulcers: chemical, toxicological and clinical analysis and therapeutic prospects

Giampietro Bertasi 1, * and Mariana Peroni 2

1 Department of Biotechnology, University of Padua, Italy.
2 Diabetology Unit, IRCCS Sacro Cuore, Negrar, Italy.
Review Article
Magna Scientia Advanced Biology and Pharmacy, 2025, 16(02), 026-033
Article DOI: 10.30574/msabp.2025.16.2.0073
DOI url: https://doi.org/10.30574/msabp.2025.16.2.0073
Received 21 October 2025; revised on 01 December 2025; accepted on 03 December 2025
Theis paper analyzes the role of p-toluenesulfonic acid (p-TsOH) in the treatment of chronic ulcers, highlighting its ability to remove bacterial biofilm and promote wound healing.
Clinical and experimental studies show that topical application of p-TsOH is effective and safe, with minimal and transient side effects, especially when used according to validated protocols.
Despite the promising results, the document emphasizes the need for further research and controlled trials to confirm the role of p-TsOH compared to other debridement strategies.
Chronic wound; p-toluenesulphonic acid; p-TsOH; CDEB; p-TsOH therapeutic prospects
https://msabp.magnascientiapub.com/sites/default/files/fulltext_pdf/MSABP-2025-…

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Giampietro Bertasi and Mariana Peroni. p-Toluene sulfonic acid, C-DEB, and chronic ulcers: chemical, toxicological and clinical analysis and therapeutic prospects. Magna Scientia Advanced Biology and Pharmacy, 2025, 16(2), 026-033. Article DOI: https://doi.org/10.30574/msabp.2025.16.2.0073

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